OVERVIEW + STUDY DETAILS

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Conceptual consensus

EWGSOP2: sarcopenia definition and assessment

In this analysis, DXA lean mass is fat-free mass minus bone mineral content. It includes tissues other than muscle and, alone, does not describe strength or diagnose sarcopenia.

Under EWGSOP2, low strength indicates probable sarcopenia; low muscle quantity or quality confirms the diagnosis, and low physical performance together with the other criteria identifies severe sarcopenia.

Evidence design
Diagnostic consensus concept

Keep in view

  • Diagnostic consensus; it does not estimate a treatment effect or individual risk.
  • A decrease in total DXA lean mass alone does not diagnose sarcopenia.
See study details — EWGSOP2

Definitions and assessment framework

Diagnostic consensus concept

Expert consensus updating the European definition and diagnostic approach to sarcopenia; not an intervention trial.

Diagnostic concepts
  • Diagnostic state
    Probable sarcopenia
    Definition
    Low muscle strength identifies probable sarcopenia.
  • Diagnostic state
    Confirmed sarcopenia
    Definition
    Low muscle quantity or quality confirms the diagnosis in the presence of low strength.
  • Diagnostic state
    Severe sarcopenia
    Definition
    Low strength, low muscle quantity/quality and low physical performance together identify severe sarcopenia.
Assessment sequence
  • Find cases
  • Assess muscle strength
  • Confirm muscle quantity or quality
  • Determine severity with physical performance

What the curated evidence supports

  • In this analysis, DXA lean mass is fat-free mass minus bone mineral content. It includes tissues other than muscle and, alone, does not describe strength or diagnose sarcopenia.
  • Under EWGSOP2, low strength indicates probable sarcopenia; low muscle quantity or quality confirms the diagnosis, and low physical performance together with the other criteria identifies severe sarcopenia.

Limitations

  • Diagnostic consensus; it does not estimate a treatment effect or individual risk.
  • A decrease in total DXA lean mass alone does not diagnose sarcopenia.

Verification scope

Verified through 2026-11-04 within the consulted scope.

Bibliographic metadata checked
Yes
Original article abstract consulted
Yes
Full-text consultation
Consulted
Official trial registry consulted
No
Statistical analysis plan consulted
No
Verification boundary
Verification is limited to the specific fields and sources consulted; it is not a full systematic appraisal or GRADE rating.

Source record

Sarcopenia: revised European consensus on definition and diagnosis (2019). Age and ageing.